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Examples include insulin, endorphins, and oxytocin
This limitation is precisely why synthetic analogues like Melanotan 1 and Melanotan 2 were developed
However, the exact mechanisms and timing underlying BBB disruption and its role in the onset and progression of disease are not yet fully understood (Nian et al., 2020)
Lack of NLRP3-inflammasome leads to gut-liver axis derangement, gut dysbiosis and a worsened phenotype in a mouse model of NAFLD
Gross R, Hurwitz R, Marks P
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